论文成果

A PSMA-targeted 68Ga probe with improved tumor-to-background contrast

J. Wu, L. Gao

European Journal of Nuclear Medicine and Molecular Imaging 53(4), 2026 · 期刊论文

A revised chelator linker reduces free gallium redistribution and improves tumor-to-background ratio in preclinical prostate cancer models without loss of binding affinity.

DOI

Quantitative correction for respiratory motion in simultaneous PET/MRI

Y. Zheng^*, Z. Shen^*, H. Nakamura, M. Su

IEEE Transactions on Medical Imaging 45(2), 2026 · 期刊论文

* 共同第一作者

A joint motion-reconstruction framework uses MRI navigators to model respiratory displacement during reconstruction rather than correcting it afterwards, reducing SUV bias in small lesions.

DOI代码

Dual-modality fluorescence guidance for intraoperative margin assessment

L. Ouyang, J. Wu

Theranostics 15, 2025 · 期刊论文

A dual-labeled probe supports both preoperative PET staging and intraoperative fluorescence guidance, enabling margin assessment within the surgical workflow.

DOI

Task-based evaluation of deep reconstruction for low-dose total-body PET

M. Su, Y. Zheng

Proceedings of MICCAI 2025, 2025 · 会议论文

Deep reconstruction methods that score well on image similarity metrics can suppress small lesions; we evaluate them with detection-task metrics instead and report the dose level at which detectability degrades.

DOI代码

In vivo stability of chelator-free radiolabeled nanoparticles

L. Gao, Y. Luo, J. Wu

Molecular Imaging and Biology 26, 2024 · 期刊论文

We characterize radionuclide release from chelator-free labeled nanoparticles and show how the resulting free-isotope redistribution shapes non-target organ uptake.

DOI数据

Reporting standards for preclinical molecular imaging studies

Y. Zheng, R. Adeyemi

Open Research Cultures, 2024 · 专著章节

This chapter argues that acquisition parameters, reconstruction settings, and calibration records are not supplementary material but a precondition for interpreting any reported quantitative value.